AA-labeling result

Russian translation: см.

17:37 Feb 25, 2020
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals / Спецификация
English term or phrase: AA-labeling result
OLIGOSACCHARIDE PROFILING
The specification for oligosaccharide profiling is ≥ 58%. The 1-sided lower limit represents the minimum carbohydrate remodeling required in order to achieve an appropriate mannose-terminated structure for sufficient macrophage targeting in vivo and thus efficacy of the final drug product and is also appropriately higher than that determined to be considered “under modified” imiglucerase (< 51.3%).
Preparation with an AA-labeling result of 49.0 - 51.3% was considered "under-modified" and not acceptable from a product quality perspective. This lower boundary of 51.3% was considered when performing statistical analysis on the AA-labeling data sets obtained to develop an appropriate specification
Olesya Poleschuk
Kazakhstan
Local time: 14:09
Russian translation:см.
Explanation:
препарат с уровнем мечения аминобейзойной кислотой 49.0-51.3%

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Note added at 1 hr (2020-02-25 18:58:40 GMT)
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некоторые используют "степень мечения"
https://ru.glance-tech.com/peptide-tag-specific-nanobody-ena...
Аппроксимация мечения олигомеров FtnA молекулами AF647 с биномиальным распределением со степенью мечения (0, 7 ± 0, 15 в случае нанотела bivBC2-Nb AF647 и 0, 95 ± 0, 05 в случае AF647-BG),

http://earthpapers.net/vzaimodeystvie-kinezina-cenp-e-i-belk...
Растворимый тубулин был мечен Hilyte647 со степенью мечения 1:15 .
Selected response from:

Marlin31
Russian Federation
Local time: 12:09
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Summary of answers provided
3см.
Marlin31


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9 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
aa-labeling result
см.


Explanation:
препарат с уровнем мечения аминобейзойной кислотой 49.0-51.3%

--------------------------------------------------
Note added at 1 hr (2020-02-25 18:58:40 GMT)
--------------------------------------------------

некоторые используют "степень мечения"
https://ru.glance-tech.com/peptide-tag-specific-nanobody-ena...
Аппроксимация мечения олигомеров FtnA молекулами AF647 с биномиальным распределением со степенью мечения (0, 7 ± 0, 15 в случае нанотела bivBC2-Nb AF647 и 0, 95 ± 0, 05 в случае AF647-BG),

http://earthpapers.net/vzaimodeystvie-kinezina-cenp-e-i-belk...
Растворимый тубулин был мечен Hilyte647 со степенью мечения 1:15 .

Marlin31
Russian Federation
Local time: 12:09
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 436
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